- William R. Aylett, Colonel of the 53rd Virginia Infantry, Great Grandson of Patrick Henry
- The Family of John Brown
- William F. "Buffalo Bill" Cody
- The Family of George Armstrong Custer
- The Descendants of Jefferson Davis
- The Earp Family
- Family Connections of Ulysses S. Grant
- The Descendants of Abraham Lincoln
- The Family of Paul Revere
- Franklin Rockefeller, younger brother of John D. Rockefeller, Sr.
- Henry Weston Smith, "Preacher Smith" of Deadwood.
- Daniel Fletcher Webster, Colonel of the 12th Massachusetts Infantry, Son of Daniel Webster
Civil War Connections to the RMS Titanic
- The Roebling Family: Brevet Colonel Washington August Roebling, who went on to build the Brooklyn Bridge was the uncle of Washington Augustus Roebling II who perished aboard the RMS Titanic.
- The Gracie Family: Confederate Brigadier-General Archibald Gracie's son, Archibald Gracie IV, authored "The Truth About Chickamauga" and survived the sinking of the RMS Titanic but died a few months later.
- The Boggs Family: Confederate General William Robertson Bogg's nephew, Major Archibald Butt, military assistant to Presidents Theodore Roosevelt and William Howard Taft, perished aboard the RMS Titanic. His body was never recovered.